Core DNA replication machinery proteins

   
Contact: Randall Shultz
Organization: North Carolina State University
Source: Shultz, RW, Tatineni, VM, Hanely-Bowdoin, L, Thompson, WF (2007) Genome-wide Analysis of the Core DNA Replication Machinery in the Higher Plants Arabidopsis thaliana and Oryza sativa. Plant Physiology 144(4):1697-714
Criteria: Core DNA replication family proteins are essential for the initiation, elongation, and Okazaki fragment maturation stages of DNA replication. The core DNA replication machinery in rice was defined based on manual inspection of protein sequence alignments to well characterized yeast and animal sequences.
   

LOC_Os01g10690

Gene Name: POLD3
Gene Description: Putative DNA polymerase delta complex subunit
MSU Annotation: POLD3 - Putative DNA polymerase delta complex subunit, expressed
Structural Annotation:  

   

LOC_Os01g14610

Gene Name: PSF2
Gene Description: Putative GINS complex subunit
MSU Annotation: PSF2 - Putative GINS complex subunit, expressed
Structural Annotation:  

   

LOC_Os01g14980

Gene Name: RPA3
Gene Description: Putative single-stranded DNA binding complex subunit 3
MSU Annotation: RPA3 - Putative single-stranded DNA binding complex subunit 3, expressed
Structural Annotation:  

   

LOC_Os01g36390

Gene Name: MCM4
Gene Description: Putative minichromosome maintenance (MCM) complex subunit 4
MSU Annotation: MCM4 - Putative minichromosome maintenance MCM complex subunit 4, expressed
Structural Annotation:  

   

LOC_Os01g49010

Gene Name: ORC4
Gene Description: Putative origin recognition complex subunit 4
MSU Annotation: ORC4 - Putative origin recognition complex subunit 4, expressed
Structural Annotation:  

   

LOC_Os01g63710

Gene Name: CDC6
Gene Description: Putative DNA replication initiation protein
MSU Annotation: CDC6 - Putative DNA replication initiation protein, expressed
Structural Annotation:  

   

LOC_Os01g64820

Gene Name: POLA1
Gene Description: Putative DNA polymerase alpha catalytic subunit
MSU Annotation: POLA1 - Putative DNA polymerase alpha catalytic subunit, expressed
Structural Annotation:  

   

LOC_Os02g30800

Gene Name: POLE1
Gene Description: Putative DNA polymerase epsilon catalytic subunit
MSU Annotation: POLE1 - Putative DNA polymerase epsilon catalytic subunit, expressed
Structural Annotation:  

   

LOC_Os02g42230

Gene Name: RPA2B
Gene Description: Putative single-stranded DNA binding complex subunit 2
MSU Annotation: RPA2B - Putative single-stranded DNA binding complex subunit 2, expressed
Structural Annotation:  

   

LOC_Os02g53500

Gene Name: RFC5
Gene Description: Putative clamp loader (of PCNA), replication factor C subunit 5
MSU Annotation: RFC5 - Putative clamp loader of PCNA, replication factor C subunit 5, expressed
Structural Annotation:  

   

LOC_Os02g53680

Gene Name: RPA1A
Gene Description: Putative single-stranded DNA binding complex subunit 1
MSU Annotation: RPA1A - Putative single-stranded DNA binding complex subunit 1, expressed
Structural Annotation:  

   

LOC_Os02g55410

Gene Name: MCM5
Gene Description: Putative minichromosome maintenance (MCM) complex subunit 5
MSU Annotation: MCM5 - Putative minichromosome maintenance MCM complex subunit 5, expressed
Structural Annotation:  

   

LOC_Os02g56130

Gene Name: PCNA
Gene Description: Putative DNA replicative polymerase clamp
MSU Annotation: PCNA - Putative DNA replicative polymerase clamp, expressed
Structural Annotation:  

   

LOC_Os02g58220

Gene Name: RPA2A
Gene Description: Putative single-stranded DNA binding complex subunit 2
MSU Annotation: RPA2A - Putative single-stranded DNA binding complex subunit 2, expressed
Structural Annotation:  

   

LOC_Os03g03650

Gene Name: POLD2
Gene Description: Putative DNA polymerase delta complex subunit
MSU Annotation: POLD2 - Putative DNA polymerase delta complex subunit, expressed
Structural Annotation:  

   

LOC_Os03g08640

Gene Name: ORC2
Gene Description: Putative origin recognition complex subunit 2
MSU Annotation: ORC2 - Putative origin recognition complex subunit 2, expressed
Structural Annotation:  

   

LOC_Os03g11540

Gene Name: RPA1B
Gene Description: Putative single-stranded DNA binding complex subunit 1
MSU Annotation: RPA1B - Putative single-stranded DNA binding complex subunit 1, expressed
Structural Annotation:  

   

LOC_Os03g19190

Gene Name: TOPBP1C
Gene Description: Similar to DNA replication protein TOPBP1 from Human
MSU Annotation: TOPBP1C - Similar to DNA replication protein TOPBP1 from, expressed
Structural Annotation:  

   

LOC_Os03g55200

Gene Name: ORC5
Gene Description: Putative origin recognition complex subunit 5
MSU Annotation: ORC5 - Putative origin recognition complex subunit 5, expressed
Structural Annotation:  

   

LOC_Os03g57870

Gene Name: RFC3
Gene Description: Putative clamp loader (of PCNA), replication factor C subunit 3
MSU Annotation: RFC3 - Putative clamp loader of PCNA, replication factor C subunit 3, expressed
Structural Annotation:  

   

LOC_Os03g61820

Gene Name: FEN1B
Gene Description: Putative flap endonuclease protein
MSU Annotation: FEN1B - Putative flap endonuclease protein, expressed
Structural Annotation:  

   

LOC_Os04g10650

Gene Name: CDT1A
Gene Description: Putative DNA replication initiation protein
MSU Annotation: CDT1A - Putative DNA replication initiation protein, expressed
Structural Annotation:  

   

LOC_Os04g48060

Gene Name: RFC2
Gene Description: Putative clamp loader (of PCNA), replication factor C subunit 2
MSU Annotation: RFC2 - Putative clamp loader of PCNA, replication factor C subunit 2, expressed
Structural Annotation:  

   

LOC_Os04g49860

Gene Name: DNA2
Gene Description: Putative DNA replication helicase 2 protein
MSU Annotation: DNA2 - Putative DNA replication helicase 2 protein, expressed
Structural Annotation:  

   

LOC_Os05g02040

Gene Name: RPA1C
Gene Description: Putative single-stranded DNA binding complex subunit 1
MSU Annotation: RPA1C - Putative single-stranded DNA binding complex subunit 1, expressed
Structural Annotation:  

   

LOC_Os05g05150

Gene Name: SLD5
Gene Description: Putative GINS complex subunit
MSU Annotation: SLD5 - Putative GINS complex subunit, expressed
Structural Annotation:  

   

LOC_Os05g06840

Gene Name: POLE2A
Gene Description: Putative DNA polymerase epsilon complex subunit
MSU Annotation: POLE2A - Putative DNA polymerase epsilon complex subunit, expressed
Structural Annotation:  

   

LOC_Os05g14590

Gene Name: MCM6
Gene Description: Putative minichromosome maintenance (MCM) complex subunit 6
MSU Annotation: MCM6 - Putative minichromosome maintenance MCM complex subunit 6, expressed
Structural Annotation:  

   

LOC_Os05g29010

Gene Name: POLA4
Gene Description: Putative DNA polymerase alpha complex subunit
MSU Annotation: POLA4 - Putative DNA polymerase alpha complex subunit, expressed
Structural Annotation:  

   

LOC_Os05g37980

Gene Name: PSF1
Gene Description: Putative GINS complex subunit
MSU Annotation: PSF1 - Putative GINS complex subunit, expressed
Structural Annotation:  

   

LOC_Os05g38850

Gene Name: MCM8
Gene Description: Putative minichromosome maintenance (MCM) family subunit 8
MSU Annotation: MCM8 - Putative minichromosome maintenance MCM family subunit 8
Structural Annotation:  

   

LOC_Os05g39850

Gene Name: MCM3
Gene Description: Putative minichromosome maintenance (MCM) complex subunit 3
MSU Annotation: MCM3 - Putative minichromosome maintenance MCM complex subunit 3, expressed
Structural Annotation:  

   

LOC_Os05g46270

Gene Name: FEN1A
Gene Description: Putative flap endonuclease protein
MSU Annotation: FEN1A - Putative flap endonuclease protein, expressed
Structural Annotation:  

   

LOC_Os06g08790

Gene Name: ORC1
Gene Description: Putative origin recognition complex subunit 1
MSU Annotation: ORC1 - Putative origin recognition complex subunit 1, expressed
Structural Annotation:  

   

LOC_Os06g11500

Gene Name: MCM9
Gene Description: Putative minichromosome maintenance (MCM) family subunit 9
MSU Annotation: MCM9 - Putative minichromosome maintenance MCM family subunit 9, expressed
Structural Annotation:  

   

LOC_Os06g30320

Gene Name: NOC3
Gene Description: Putative nucleolar complex subunit 3
MSU Annotation: NOC3 - Putative nucleolar complex subunit 3, expressed
Structural Annotation:  

   

LOC_Os06g47830

Gene Name: RPA2C
Gene Description: Putative single-stranded DNA binding complex subunit 2
MSU Annotation: RPA2C - Putative single-stranded DNA binding complex subunit 2, expressed
Structural Annotation:  

   

LOC_Os07g22400

Gene Name: POLA3
Gene Description: Putative DNA polymerase alpha complex subunit
MSU Annotation: POLA3 - Putative DNA polymerase alpha complex subunit, expressed
Structural Annotation:  

   

LOC_Os07g43540

Gene Name: ORC6
Gene Description: Putative origin recognition complex subunit 6
MSU Annotation: ORC6 - Putative origin recognition complex subunit 6, expressed
Structural Annotation:  

   

LOC_Os07g49010

Gene Name: TOPBP1B
Gene Description: Similar to DNA replication protein TOPBP1 from Human
MSU Annotation: TOPBP1B - Similar to DNA replication protein TOPBP1 from, expressed
Structural Annotation:  

   

LOC_Os08g17294

Gene Name: PSF3
Gene Description: Putative GINS complex subunit
MSU Annotation: PSF3 - Putative GINS complex subunit, expressed
Structural Annotation:  

   

LOC_Os08g36330

Gene Name: POLE2B
Gene Description: Putative DNA polymerase epsilon complex subunit
MSU Annotation: POLE2B - Putative DNA polymerase epsilon complex subunit, expressed
Structural Annotation:  

   

LOC_Os08g43080

Gene Name: POLD4B
Gene Description: Putative DNA polymerase delta complex subunit
MSU Annotation: POLD4B - Putative DNA polymerase delta complex subunit
Structural Annotation:  

   

LOC_Os09g34850

Gene Name: POLD4A
Gene Description: Putative DNA polymerase delta complex subunit
MSU Annotation: POLD4A - Putative DNA polymerase delta complex subunit, expressed
Structural Annotation:  

   

LOC_Os09g36820

Gene Name: MCM10
Gene Description: Putative minichromosome maintenance (MCM) protein 10
MSU Annotation: MCM10 - Putative minichromosome maintenance MCM protein 10, expressed
Structural Annotation:  

   

LOC_Os10g26280

Gene Name: ORC3
Gene Description: Putative origin recognition complex subunit 3
MSU Annotation: ORC3 - Putative origin recognition complex subunit 3, expressed
Structural Annotation:  

   

LOC_Os10g34750

Gene Name: LIG1
Gene Description: Putative DNA ligase I
MSU Annotation: LIG1 - Putative DNA ligase I, expressed
Structural Annotation:  

   

LOC_Os10g34820

Gene Name: CDT1B
Gene Description: Putative DNA replication initiation protein
MSU Annotation: CDT1B - Putative DNA replication initiation protein, expressed
Structural Annotation:  

   

LOC_Os11g03430

Gene Name: CDC45B
Gene Description: Putative DNA replication initiation protein
MSU Annotation: CDC45B - Putative DNA replication initiation protein, expressed
Structural Annotation:  

   

LOC_Os11g05570

Gene Name: RNASEH2A
Gene Description: Putative ribonuclease H2 large subunit
MSU Annotation: RNASEH2A - Putative ribonuclease H2 large subunit, expressed
Structural Annotation:  

   

LOC_Os11g08330

Gene Name: POLD1
Gene Description: Putative DNA polymerase delta catalytic subunit
MSU Annotation: POLD1 - Putative DNA polymerase delta catalytic subunit, expressed
Structural Annotation:  

   

LOC_Os11g08660

Gene Name: TOPBP1A
Gene Description: Similar to DNA replication protein TOPBP1 from Human
MSU Annotation: TOPBP1A - Similar to DNA replication protein TOPBP1 from, expressed
Structural Annotation:  

   

LOC_Os11g29380

Gene Name: MCM2
Gene Description: Putative minichromosome maintenance (MCM) complex subunit 2
MSU Annotation: MCM2 - Putative minichromosome maintenance MCM complex subunit 2, expressed
Structural Annotation:  

   

LOC_Os11g36390

Gene Name: RFC1
Gene Description: Putative clamp loader (of PCNA), replication factor C subunit 1
MSU Annotation: RFC1 - Putative clamp loader of PCNA, replication factor C subunit 1, expressed
Structural Annotation:  

   

LOC_Os12g03130

Gene Name: CDC45A
Gene Description: Putative DNA replication initiation protein
MSU Annotation: CDC45A - Putative DNA replication initiation protein, expressed
Structural Annotation:  

   

LOC_Os12g07720

Gene Name: RFC4
Gene Description: Putative clamp loader (of PCNA), replication factor C subunit 4
MSU Annotation: RFC4 - Putative clamp loader of PCNA, replication factor C subunit 4, expressed
Structural Annotation:  

   

LOC_Os12g13950

Gene Name: POLA2
Gene Description: Putative DNA polymerase alpha complex subunit
MSU Annotation: POLA2 - Putative DNA polymerase alpha complex subunit, expressed
Structural Annotation:  

   

LOC_Os12g37400

Gene Name: MCM7
Gene Description: Putative minichromosome maintenance (MCM) complex subunit 7
MSU Annotation: MCM7 - Putative minichromosome maintenance MCM complex subunit 7, expressed
Structural Annotation:  

 

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This work is supported by grants (DBI-0321538/DBI-0834043) from the National Science Foundation and funds from the Georgia Research Alliance, Georgia Seed Development, and University of Georgia.