Maternally Expressed Gene (MEG) family protein precursor
| Superfamily: | Cysteine Rich Peptides |
| Contact: | Kevin Silverstein |
| Organization: | University of Minnesota |
| Source: | Silverstein, K.A.T., Moskal, W.A., Jr., Wu, H., Underwood, B.A., Graham, M.A., Town, C.D, and VandenBosch, K.A. (2007) Small cysteine peptides resembling antimicrobial peptides have been under-predicted in plants. Plant J. 51(2):262-80 |
| Criteria: | Iterative HMM family-based searches, starting with known cysteine-rich antimicrobial sequences. |
| Gene Name: | MEGL2 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, putative |
| Comment: | Pseudogene. Community annotation high confidence pseudogene possesses a non-canonical splice site donor, but is very similar to a half-dozen paralogs some of them nearby in this cluster. |
| Structural Annotation: | |
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| Gene Name: | MEGL4 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, putative |
| Comment: | Community annotation is a high confidence prediction is very similar to a half-dozen paralogs some of them nearby in this cluster. |
| Structural Annotation: | |
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| Gene Name: | MEGL6 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, putative |
| Comment: | Community annotation is a high confidence prediction is very similar to a half-dozen paralogs some of them nearby in this cluster. |
| Structural Annotation: | |
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| Gene Name: | MEGL1 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, putative |
| Comment: | Pseudogene. Community annotation fits nicely with close paralogs and homologs from other species |
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| Gene Name: | MEGL15 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, putative |
| Comment: | The community annotation has a hybrid cysteine configuration between a defensin and MEG family gene |
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| Gene Name: | MEGL16 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, putative |
| Comment: | Community annotation structure has high confidence based on alignment with neighboring paralog and numerous homologs from other grasses. |
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| Gene Name: | MEGL17 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, putative |
| Comment: | Pseudogene. Highly similar to neighboring paralog and numerous homologs from other grasses, but lacks a signal peptide. |
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| Gene Name: | MEGL19 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, putative |
| MSU Annotation: | MEGL19 - Maternally expressed gene MEG family protein precursor, putative |
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| Gene Name: | MEGL13 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, expressed |
| MSU Annotation: | MEGL13 - Maternally expressed gene MEG family protein precursor, expressed |
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| Gene Name: | MEGL14 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, putative |
| MSU Annotation: | MEGL14 - Maternally expressed gene MEG family protein precursor, putative, expressed |
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| Gene Name: | MEGL7 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, putative |
| MSU Annotation: | MEGL7 - Maternally expressed gene MEG family protein precursor, putative |
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| Gene Name: | MEGL8 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor |
| MSU Annotation: | MEGL8 - Maternally expressed gene MEG family protein precursor |
| Comment: | Community annotation possesses a revised acceptor site for the second intron and removes third exon. Corrected gene perfectly matches 2 neighboring homologs. |
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| Gene Name: | MEGL10 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor |
| MSU Annotation: | MEGL10 - Maternally expressed gene MEG family protein precursor |
| Comment: | Community annotation includes first 12 bp (4 aa) of signal peptide. |
| Structural Annotation: | |
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| Gene Name: | MEGL11 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor |
| MSU Annotation: | MEGL11 - Maternally expressed gene MEG family protein precursor |
| Comment: | Community annotation has a revised acceptor site for the second intron and removes the third exon. Community annotation structure perfectly matches 4 neighboring paralogs. |
| Structural Annotation: | |
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| Gene Name: | MEGL9 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, putative |
| MSU Annotation: | MEGL12 - Maternally expressed gene MEG family protein precursor |
| Comment: | Pseudogene. The community annotation possesses a non-canonical acceptor site based on alignment with 2 close paralogs surrounding it. |
| Structural Annotation: | |
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| Gene Name: | MEGL12 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor |
| MSU Annotation: | MEGL12 - Maternally expressed gene MEG family protein precursor |
| Comment: | Community annotation has a revised acceptor site for the second intron and removes the third exon. Community annotation structure perfectly matches 4 neighboring paralogs. |
| Structural Annotation: | |
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| Gene Name: | MEGL18 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, putative |
| MSU Annotation: | MEGL18 - Maternally expressed gene MEG family protein precursor, putative |
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| Gene Name: | MEGL3 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, putative |
| MSU Annotation: | MEGL3 - Maternally expressed gene MEG family protein precursor, putative |
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| Gene Name: | MEGL5 |
| Gene Description: | Maternally expressed gene (MEG) family protein precursor, putative |
| MSU Annotation: | MEGL5 - Maternally expressed gene MEG family protein precursor, putative, expressed |
| Structural Annotation: | |
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This work is supported by grants (DBI-0321538/DBI-0834043) from the National Science Foundation and funds from the Georgia Research Alliance, Georgia Seed Development, and University of Georgia.